Catheterization Laboratory Activation Time in Patients Transferred With ST-Segment–Elevation Myocardial Infarction: Insights From the Mission: Lifeline STEMI Accelerator-2 Project
Why the study?
To determine whether faster catheterization laboratory activation time is associated with improved reperfusion time and outcomes in transferred STEMI patients.
Does timely catheterization laboratory activation (≤20 minutes) improve reperfusion times in patients with STEMI requiring inter-hospital transfer for primary PCI?
Population
2063 STEMI patients requiring inter-hospital transfer for primary PCI from 12 US regions
Comparison
Timely cath lab activation (within 20 minutes) vs delayed activation (beyond 20 minutes)
Design
Multicenter observational study
Authors
Discussion
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Member takes
Implication
Faster cath lab activation may shorten reperfusion in transferred STEMI; hypothesis-generating and requires prospective validation before practice change.
Structured PICO
Does timely catheterization laboratory activation (≤20 minutes) improve reperfusion times in patients with STEMI requiring inter-hospital transfer for primary PCI?
P
Population
2,063 patients with ST-segment-elevation myocardial infarction (STEMI) requiring inter-hospital transfer for primary percutaneous coronary intervention (PCI) from 12 regions around the United States.
I
Intervention
Timely catheterization laboratory activation (within 20 minutes of first hospital arrival)
C
Comparator
Delayed catheterization laboratory activation (beyond 20 minutes)
O
Outcome
Reperfusion time and door-in door-out timessurrogate
Catheterization laboratory activation within 20 minutes for STEMI patients requiring inter-hospital transfer is associated with significantly shorter reperfusion times and a higher likelihood of meeting the national goal of ≤120 minutes.
Cite This Study
Zeitouni et al. (2020) studied this question.