Why the study?
Can medical management be a viable alternative to surgery for elderly patients with calcified left atrial myxoma who are at high surgical risk?
Can medical management be a viable alternative to surgery for elderly patients with calcified left atrial myxoma who are at high surgical risk?
This case illustrates that calcified left atrial myxoma may exhibit a quiescent phase and can be managed medically in high-risk elderly patients.
May support medical management in select high-risk elderly patients; leaves open need for prospective confirmation.
Left atrial myxoma, if left untreated, is inexorably progressive and usually fatal. The classical management of this disease is prompt surgical removal. However, there may be exceptions to this traditional dogma. The authors report an 85-year-old man who presented with features of chronic obstructive airway disease and congestive heart failure 15 years previously. Auscultation of the heart showed a pansystolic murmur. Two-dimensional echocardiography revealed a nonobstructive, calcified, and well circumscribed mass in the left atrium, with a pedicle attached to the interatrial septum. Because the patient refused high-risk cardiac surgery related to his comorbidity, he was managed medically with a bronchodilator, diuretics, and digoxin. There have been no features of embolism or intracardiac obstruction, and serial echocardiography demonstrates no disease progression over this long period of time. This case illustrates that calcified left atrial myxoma may exhibit a quiescent phase. Tumor calcification, slow growth potential, and the absence of intracardiac obstruction may correlate with a better outcome in the elderly patient.
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Kay et al. (2002) studied this question.
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