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January 1, 1992Journal of Computer Assisted Tomography

Sedation for Pediatric Patients Undergoing CT and MRI

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Why the study?

Are sedation protocols using chloral hydrate and intravenous pentobarbital safe and effective in pediatric patients undergoing CT and MRI?

Population

1,158 children between the ages of 1 day and 18 years undergoing CT and MRI

Design

Cohort

Authors

AHAnne M. HubbardAmerican Society for Radiation OncologyRMRichard I. MarkowitzChildren's Hospital of PhiladelphiaBKBarbara KimmelBaylor College of Medicine

Discussion

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Implication

Supports feasibility of these regimens for pediatric imaging; hypothesis-generating and requires randomized trials before practice change.

Structured PICO

Are sedation protocols using chloral hydrate and intravenous pentobarbital safe and effective in pediatric patients undergoing CT and MRI?

P
Population
1,158 children between the ages of 1 day and 18 years undergoing CT and MRI
I
Intervention
Sedation protocols including chloral hydrate (60-120 mg/kg by mouth) for infants less than 18 months and intravenous pentobarbital (2-6 mg/kg) for older children
O
Outcome
Safety and efficacy (sedation success)safety

Sedation protocols using chloral hydrate for infants and intravenous pentobarbital for older children are highly effective (97% success) for pediatric cross-sectional imaging.

Cite This Study

Hubbard et al. (1992) studied this question.

synapsesocial.com/papers/6a712759e36a167817e2faechttps://doi.org/10.1097/00004728-199201000-00002
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effective Sedation Strategies for Pediatric MRI: A Comprehensive Analysis2024
  2. 2Sedation in pediatric CT: national survey of current practice.1990 · 100 citations
  3. 3The choice of sedation for computed tomography in children: a prospective evaluation.1982 · 64 citations
  4. 4Safe Pediatric Outpatient Sedation: The Chloral Hydrate Debate Revisited1997 · 25 citations
  5. 5Sedation for radiological imaging2010 · 37 citations