Why the study?
Does maintenance of deep brain stimulation using externalized electrodes and an extracorporeal pulse generator allow infection clearance in patients with severe dystonia and implant infection?
Does maintenance of deep brain stimulation using externalized electrodes and an extracorporeal pulse generator allow infection clearance in patients with severe dystonia and implant infection?
Prolonged extracorporeal stimulation using externalized electrodes can maintain deep brain stimulation while allowing infection clearance in severe dystonia.
Answers are grounded in this paper and cite their sources.
May allow infection clearance without explantation in severe dystonia; hypothesis-generating and requires validation in larger cohorts.
Infection in the context of implant surgery is a dreaded complication, usually necessitating the removal of all affected hardware. Severe dystonia is a debilitating condition that can present as an emergency and can occasionally be life threatening. The authors present 2 cases of severe dystonia in which deep brain stimulation was maintained despite the presence of infection, using ongoing stimulation by externalization of electrode wires and an extracorporeal pulse generator. This allowed the infection to clear and wounds to heal while maintaining stimulation. This strategy is similar to that used in the management of infected cardiac pacemakers. The authors suggest that this prolonged extracorporeal stimulation should be considered by neurosurgeons in the face of this difficult clinical situation.
No takes yet. Share an insight, caveat, or question.
Hyam et al. (2009) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: