Why the study?
Does the presence of elevated jugular venous pressure or a third heart sound on physical examination predict adverse outcomes in patients with chronic heart failure?
Does the presence of elevated jugular venous pressure or a third heart sound on physical examination predict adverse outcomes in patients with chronic heart failure?
Simple physical examination findings, specifically elevated jugular venous pressure and a third heart sound, provide important independent prognostic information in patients with chronic heart failure.
Supports routine JVP and S3 assessment for prognostication in chronic HF; extends prior observations but leaves open prospective validation.
The importance placed on the physical examination in the assessment of patients with cardiovascular disorders appears to be declining, perhaps in part due to a paucity of data showing its value in the modern era. To determine whether the physical examination provides important prognostic information in patients with chronic heart failure, the authors performed a post-hoc analysis of 2479 participants from the Studies of Left Ventricular Dysfunction (SOLVD) treatment trial. The presence of elevated jugular venous pressure and a third heart sound at baseline were each associated with subsequent heart failure hospitalization, the composite end point of death or heart failure hospitalization, and pump-failure death, independently of many other markers of disease severity. The subgroup of patients with at least one of these two physical examination findings was at increased risk for all-cause mortality. The authors believe that additional studies assessing the prognostic value of the physical examination should be conducted and, if favorable, likely would lead to a renewed interest in the physical examination.
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Rame et al. (2003) studied this question.
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