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January 1, 1985StrokeOpen Access

Serum HDL/total cholesterol ratio and blood pressure in asymptomatic atherosclerotic lesions of the cervical carotid arteries in men.

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Population

100 neurologically asymptomatic male subjects, randomly selected through population registers. 93 subjects…

Design

Cross-sectional

Authors

TMTiny Van MerodeMaastricht University PHPaul J.J. HickMaastricht University PHP G Hoeks

Discussion

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Implication

Low HDL/total cholesterol ratio and hypertension were associated with asymptomatic carotid lesions; leaves open whether modification alters progression in asymptomatic men.

Key Points

The aim is to investigate the relationship between serum HDL/total cholesterol ratio and blood pressure in men with asymptomatic atherosclerotic lesions of the cervical carotid arteries.
One hundred neurologically asymptomatic male subjects aged 50-69 years were screened for cervical carotid artery lesions using Doppler imaging.
Serum was analyzed for total and HDL cholesterol levels, and arterial blood pressure was measured.
Subjects were categorized into three groups based on the presence of atherosclerotic lesions and clinical history.
23% of screened subjects exhibited asymptomatic atherosclerotic lesions of the cervical carotid arteries.
Groups II and III had a lower HDL/total cholesterol ratio and a higher frequency of high blood pressure compared to Group I.
A significant association was found between low serum HDL/total cholesterol ratio and high blood pressure with the presence of carotid artery narrowing.

Structured PICO

P

Population

100 neurologically asymptomatic male subjects (aged 50-69 years), randomly selected through population registers. 93 subjects were assayed for total and HDL cholesterol.

O

Outcome

Presence of asymptomatic atherosclerotic lesions of the cervical carotid arteries assessed by high resolution multi-gate pulsed Doppler systemsurrogate

A low serum HDL/total cholesterol ratio and high blood pressure are associated with early, asymptomatic atherosclerotic lesions of the cervical carotid arteries in men.

Cite This Study

Merode et al. (1985) studied this question.

synapsesocial.com/papers/6a712bb7e5469ee92be1c675 https://doi.org/10.1161/01.str.16.1.34

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Also Consider

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1Evaluation of Carotid Bifurcation Disease1982 · 37 citations
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5A Multigate Pulsed Doppler System with Serial Data Processing1981 · 68 citations