What question did this study set out to answer?

To assess the clinical prognosis of asymptomatic ulcerated carotid bifurcation plaques and evaluate the necessity of prophylactic surgical intervention.

November 1, 1980Archives of Surgery

Prognosis of Asymptomatic Ulcerating Carotid Lesions

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Authors

JKJohn M. KroenerLa Jolla Alcohol Research

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Implication

Cohort study reveals a low seven-year stroke rate of one percent in asymptomatic ulcerated carotid plaque, indicating prophylactic surgery is not justified.

Key Points

To assess the clinical prognosis of asymptomatic ulcerated carotid bifurcation plaques and evaluate the necessity of prophylactic surgical intervention.
Angiographic identification and longitudinal follow-up (96% follow-up rate, mean duration of 3 years) of 79 patients harboring 91 asymptomatic ulcerated carotid plaques.
Lesions were stratified into small (n=63 in 55 patients) and large (n=24 in 21 patients) ulcerations and tracked for ischemic events using life-table analysis over up to 7 years.
The cumulative stroke rate calculated by life-table analysis was 1% at 7 years.
Small lesions led to transient ischemic attacks in 3 patients and stroke in 1 (7% cumulative symptom rate), whereas large lesions led to transient ischemic attacks in 1 patient (9%) and no strokes, showing no significant subgroup differences.
Cumulative all-cause mortality reached 17% at 3 years and 52% at 7 years, with no significant differences observed across lesion subgroups.

Cite This Study

John M. Kroener (1980) studied this question.

synapsesocial.com/papers/6a7bc4f1a540d02696c29b94 https://doi.org/10.1001/archsurg.1980.01380110119019

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Implication

Cohort study reveals a low seven-year stroke rate of one percent in asymptomatic ulcerated carotid plaque, indicating prophylactic surgery is not justified.

Prognosis of Asymptomatic Ulcerating Carotid Lesions

Discussion

Member takes

Implication

Key Points

Cite This Study

Prognosis of Asymptomatic Ulcerating Carotid Lesions

Discussion

Member takes

Implication

Key Points

Cite This Study

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Also Consider