Why the study?
Does carotid endarterectomy reduce the annual incidence of stroke compared to medical therapy in patients with carotid bifurcation atherosclerosis?
Population
619 patients with carotid bifurcation atherosclerosis undergoing 993 carotid endarterectomies at a single…
Comparison
Carotid endarterectomy vs Historical literature controls receiving optimal…
Design
Cohort
Follow-up
Long-term (since 1970)
Authors
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Supports lower stroke rates after CEA versus historical controls in this cohort; leaves open randomized confirmation against contemporary medical therapy.
Does carotid endarterectomy reduce the annual incidence of stroke compared to medical therapy in patients with carotid bifurcation atherosclerosis?
Carotid endarterectomy with low perioperative complication rates appears superior to medical therapy for stroke prevention in symptomatic and selected asymptomatic patients with carotid atherosclerosis.
Callow et al. (1989) studied this question.
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