Why the study?
Does the use of migraine abortive agents (sumatriptan, dihydroergotamine) in patients on serotomimetic prophylaxis cause serotonin syndrome?
Does the use of migraine abortive agents (sumatriptan, dihydroergotamine) in patients on serotomimetic prophylaxis cause serotonin syndrome?
The combination of migraine abortive agents and serotomimetic prophylactic agents can precipitate transient serotonin syndrome.
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May warrant caution with these combinations; hypothesis-generating case series leaves open true incidence and need for prospective data.
Nt et al. (1996) studied this question.
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