July 4, 2017Journal of Cardiovascular Electrophysiology

Interlead heterogeneity of R‐ and T‐wave morphology in standard 12‐lead ECGs predicts sustained ventricular tachycardia/fibrillation and arrhythmic death in patients with cardiomyopathy

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Why the study?

Does elevated interlead R- and T-wave heterogeneity on 12-lead ECG predict sustained ventricular arrhythmias and arrhythmic death in patients with cardiomyopathy?

Population

120 consecutive patients without an apparent reversible trigger for ventricular tachycardia, recent…

Comparison

Elevated R-wave heterogeneity and/or T-wave… vs Absence of elevated RWH and/or TWH

Design

Cohort

Authors

ATAlex Y. TanElectrophysiology BNBruce D. NearingElectrophysiology MRMichael A. RosenbergGeneral Cardiology

Discussion

Member takes

Implication

Observational data link repolarization nonuniformity to VT; leaves open need for prospective validation before risk-stratification use.

Structured PICO

Does elevated interlead R- and T-wave heterogeneity on 12-lead ECG predict sustained ventricular arrhythmias and arrhythmic death in patients with cardiomyopathy?

Population

120 consecutive patients without an apparent reversible trigger for ventricular tachycardia (VT), recent myocardial infarction, or active ischemia, who presented for electrophysiologic study, implantable cardioverter defibrillator (ICD) placement, or generator change.

Intervention

Elevated R-wave heterogeneity (RWH >160 μV) and/or T-wave heterogeneity (TWH >80 μV) on standard 12-lead ECG

Comparator

Absence of elevated RWH and/or TWH

Outcome

Sustained VT/ventricular fibrillation (VF) or appropriate ICD therapieshard clinical

Interlead R- and T-wave heterogeneity on standard 12-lead ECGs can independently predict sustained ventricular arrhythmias and arrhythmic death in patients with cardiomyopathy.

Cite This Study

Tan et al. (2017) studied this question.

synapsesocial.com/papers/6a713b2c8031ec7bb1dcd66d https://doi.org/10.1111/jce.13288

Topics

Ventricular arrhythmias Cardiomyopathy Cardiac device therapy

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Interlead heterogeneity of R‐ and T‐wave morphology in standard 12‐lead ECGs predicts sustained ventricular tachycardia/fibrillation and arrhythmic death in patients with cardiomyopathy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Interlead heterogeneity of R‐ and T‐wave morphology in standard 12‐lead ECGs predicts sustained ventricular tachycardia/fibrillation and arrhythmic death in patients with cardiomyopathy

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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