Why the study?
Overt hypothyroidism is uncommon in Hashimoto thyroiditis, and severe hypothyroidism leading to rhabdomyolysis represents an unusual clinical presentation.
Highlights a rare presentation of severe hypothyroidism due to Hashimoto's thyroiditis resulting in rhabdomyolysis.
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Case of rhabdomyolysis in severe hypothyroid Hashimoto's warrants CK monitoring in symptomatic patients; leaves open need for prospective studies on prevalence and screening.
Hashimoto's thyroiditis, a chronic autoimmune inflammation of the thyroid glands, is the most common cause of hypothyroidism in iodine-sufficient areas, which can have varied clinical manifestations. It is more common in females and usually has an insidious course. Most patients present with mild clinical symptoms, such as constipation, fatigue, and weakness. Symptoms are associated with a slight increase in thyroid-stimulating hormone (TSH) levels and the presence of thyroid antibodies. However, overt hypothyroidism is uncommon. We hereby present an interesting case of rhabdomyolysis secondary to severe hypothyroidism due to Hashimoto's thyroiditis.
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Munankami et al. (2023) studied this question.
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