Why the study?
Is the REN gene rs1464816 polymorphism associated with chronic kidney disease progression in ADPKD patients?
Population
102 ADPKD patients and 106 healthy controls from the same geographic area
Comparison
REN gene tag-SNPs vs Healthy controls and alternative genotypes
Design
Case-control
Authors
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REN polymorphisms may modify ADPKD progression; leaves open clinical utility pending validation in prospective cohorts.
Is the REN gene rs1464816 polymorphism associated with chronic kidney disease progression in ADPKD patients?
The rs1464816 polymorphism in the REN gene is associated with an increased risk of CKD progression in patients with ADPKD.
Ramanathan et al. (2016) studied this question.
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