Why the study?
The ESC 0/1-hour algorithm has been primarily validated in Europe, America, and Australasia, with less knowledge of its performance outside these settings.
Does the European Society of Cardiology 0/1-hour algorithm accurately diagnose index myocardial infarction in patients evaluated for MI?
Population
11 014 patients from 10 cohorts
Comparison
ESC 0/1 hour algorithm based on hs-cTnT (Roche), hs-cTnI (Abbott), and hs-cTnI (Siemens)
Design
Systematic review and bivariate random-effects meta-analysis
Authors
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May warrant caution in Asian EDs if <1% MI miss rate required; extends validation beyond Western cohorts but leaves practice change open.
Does the European Society of Cardiology 0/1-hour algorithm accurately diagnose index myocardial infarction in patients evaluated for MI?
The ESC 0/1-hour algorithm for MI diagnosis has high accuracy but may not meet the safety threshold of a <1% miss rate.
Chiang et al. (2020) studied this question.
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