June 1, 1992FEBS LettersOpen Access

Thermal denaturation of the alkali light chain‐20 kDa fragment complex obtained from myosin subfragment 1

View Full Paper

Ask AI

Bookmark

Population

Myosin subfragment 1 (S1) from rabbit skeletal muscle and its derivatives obtained by tryptic digestion

Design

Preclinical

Authors

Discussion

Localizes myosin S1's most thermostable domain to the C-terminal 20 kDa segment; extends structural insights but leaves clinical translation open.

Population

Myosin subfragment 1 (S1) from rabbit skeletal muscle and its derivatives obtained by tryptic digestion

Intervention

Thermal denaturation studied by differential scanning calorimetry and thermal gel analysis

Outcome

Thermal transitions and melting of thermostable domains

The most thermostable domain in the myosin S1 molecule is located in the C-terminal 20 kDa segment of the S1 heavy chain.

Golitsina et al. (1992) studied this question.

View Full Paper

Ask AI

Bookmark

Localizes myosin S1's most thermostable domain to the C-terminal 20 kDa segment; extends structural insights but leaves clinical translation open.