Potassium channels in cultured bovine adrenal chromaffin cells.
Population
Cultured bovine adrenal chromaffin cells
Design
Preclinical
Authors
Discussion
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Implication
These bovine cell findings warrant no clinical extrapolation; leaves open channel roles in human adrenal or cardiovascular Ca2+ signaling.
Structured PICO
P
Population
Cultured bovine adrenal chromaffin cells
I
Intervention
Patch-clamp techniques with various calcium buffers (EGTA, BAPTA) and ionic conditions
O
Outcome
Characterization of potassium channel currents and unitary conductancessurrogate
Identified and characterized three distinct potassium channels (BK, FK, SK) in bovine adrenal chromaffin cells, highlighting the superior calcium buffering efficiency of BAPTA over EGTA.
Cite This Study
Marty et al. (1985) studied this question.