Why the study?
The optimal procedural endpoint of catheter ablation for the treatment of inappropriate sinus tachycardia has not yet been identified.
Does sinus node ablation aiming at change in P-wave morphology from an inferior to a superior axis improve outcomes in patients with highly symptomatic inappropriate sinus tachycardia?
Does sinus node ablation aiming at change in P-wave morphology from an inferior to a superior axis improve outcomes in patients with highly symptomatic inappropriate sinus tachycardia?
Targeting a change in P-wave morphology from an inferior to a superior axis during sinus node ablation may be an effective procedural endpoint for inappropriate sinus tachycardia.
Answers are grounded in this paper and cite their sources.
Does not yet support routine adoption of P-wave morphology change as ablation endpoint in IST; leaves open its role pending higher-level evidence.
Key Teaching Points•The optimal procedural endpoint of catheter ablation for the treatment of inappropriate sinus tachycardia has not yet been identified.•Among patients with highly symptomatic inappropriate sinus tachycardia, sinus node ablation aiming at change in P-wave morphology from an inferior to a superior axis appears to be an effective treatment.•Considering the change in P-wave morphology from an inferior to a superior axis as targeted procedural endpoint can be effective even for patients who did not respond to sinus node modification. •The optimal procedural endpoint of catheter ablation for the treatment of inappropriate sinus tachycardia has not yet been identified.•Among patients with highly symptomatic inappropriate sinus tachycardia, sinus node ablation aiming at change in P-wave morphology from an inferior to a superior axis appears to be an effective treatment.•Considering the change in P-wave morphology from an inferior to a superior axis as targeted procedural endpoint can be effective even for patients who did not respond to sinus node modification.
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Reißmann et al. (2019) studied this question.
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