Why the study?
Does labetalol reduce indices of myocardial necrosis in patients with suspected acute myocardial infarction?
Population
166 patients admitted to a cardiac care unit with suspected acute myocardial infarction, age ≤75 years.
Comparison
Labetalol. vs Conventional therapy.
Design
RCT, Randomised
Follow-up
5 days
Authors
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Labetalol should not be used routinely in normotensive suspected AMI; challenges benefit on myocardial necrosis indices.
Does labetalol reduce indices of myocardial necrosis in patients with suspected acute myocardial infarction?
Labetalol cannot be recommended as routine treatment for normotensive patients admitted with suspected myocardial infarction due to increased CKMB release and dose limitations from hypotension.
Heber et al. (1987) studied this question.
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