What question did this study set out to answer?

To evaluate the long-term actuarial survival and specific failure mechanisms of endocardial pacing leads in a pediatric and young adult population.

July 1, 1993Pacing and Clinical Electrophysiology

Actuarial Survival of Transvenous Pacing Leads in a Pediatric Population

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Why the study?

Does atrial versus ventricular placement affect the actuarial survival of endocardial pacing leads in a pediatric and young adult population?

Population

148 children and young adults age 4 months to 38 years requiring endocardial pacing leads.

Comparison

Endocardial pacing leads (atrial placement) vs Endocardial pacing leads (ventricular placement)

Design

Cohort

Follow-up

5 years

Authors

YLYung R. LauUniversity of Alabama at Birmingham PGPaul C. GillettePediatric / Congenital Cardiology DBDavid S. BucklesBC Cancer Agency

Discussion

Member takes

Implication

May warrant closer atrial lead surveillance in young patients; leaves open optimal selection strategies pending prospective data.

Key Points

To evaluate the long-term actuarial survival and specific failure mechanisms of endocardial pacing leads in a pediatric and young adult population.
Prospectively followed 148 children and young adults (aged 4 months to 38 years) with normal cardiac anatomy (n=58) or surgically corrected congenital heart disease (n=90).
Evaluated 213 implanted transvenous pacing leads for survival over a 5-year follow-up period using actuarial curves.
Identified risk factors and associations with lead abandonment using stepwise discriminant analysis.
Actuarial analysis showed that 76.0% of transvenous pacemaker leads remained functional and in use at 5 years.
Atrial pacing leads exhibited significantly higher rates of abandonment compared to ventricular leads (30 vs 5 abandoned leads; P < 0.0005).
Lead insulation material, underlying cardiac anatomy, and clinical indication for pacing had no statistically significant impact on lead survival.

Structured PICO

Does atrial versus ventricular placement affect the actuarial survival of endocardial pacing leads in a pediatric and young adult population?

Population

148 children and young adults age 4 months to 38 years (58 with normal cardiac anatomy, 90 with surgically corrected congenital heart disease) requiring endocardial pacing leads.

Intervention

Endocardial pacing leads (atrial placement)

Comparator

Endocardial pacing leads (ventricular placement)

Outcome

Actuarial survival of endocardial pacing leads at 5 yearshard clinical

In a pediatric and young adult population, 76% of endocardial pacing leads survive at 5 years, with atrial leads having a significantly higher abandonment rate than ventricular leads.

Cite This Study

Lau et al. (1993) studied this question.

synapsesocial.com/papers/6a7151cca7fbea1e44086033 https://doi.org/10.1111/j.1540-8159.1993.tb01729.x

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Actuarial Survival of Transvenous Pacing Leads in a Pediatric Population

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Actuarial Survival of Transvenous Pacing Leads in a Pediatric Population

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Also Consider

Also Consider