December 1, 1987The Journal of PhysiologyOpen Access

Pharmacological and physiological properties of the after‐hyperpolarization current of bullfrog ganglion neurones.

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Population

Bullfrog ganglion B cells (neurones)

Design

Preclinical

Authors

JGJ. W. GohUniversity of British Columbia PPPeter PennefatherUniversity of Toronto

Discussion

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Implication

Preclinical IAHP findings in bullfrog neurons warrant no clinical application; leaves open their role in mammalian autonomic spike adaptation.

Structured PICO

Population

Bullfrog ganglion B cells (neurones)

Intervention

Pharmacological agents (muscarine, charybdotoxin, apamin, (+)-tubocurarine) and varying extracellular calcium levels

Outcome

Properties of the after-hyperpolarization current (IAHP) including decay time and amplitudesurrogate

This preclinical study elucidates the pharmacological sensitivities and physiological roles of calcium-dependent potassium currents (IAHP and Ic) in bullfrog ganglion neurons.

Cite This Study

Goh et al. (1987) studied this question.

synapsesocial.com/papers/6a7151fbfe4101aa97e08595 https://doi.org/10.1113/jphysiol.1987.sp016872

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Implication

Preclinical IAHP findings in bullfrog neurons warrant no clinical application; leaves open their role in mammalian autonomic spike adaptation.

Pharmacological and physiological properties of the after‐hyperpolarization current of bullfrog ganglion neurones.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Pharmacological and physiological properties of the after‐hyperpolarization current of bullfrog ganglion neurones.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider