Why the study?
Only few clinical studies have evaluated the effects of levosimendan on cardiac function using echocardiography.
Does levosimendan improve echocardiographic parameters of ventricular systolic and diastolic functions in heart failure patients?
Population
574 heart failure patients across 29 randomized controlled trials
Comparison
Levosimendan evaluated across trials
Design
Meta-analysis of randomized controlled trials
Authors
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Supports levosimendan for biventricular function improvement in HF; extends sparse echocardiographic RCT data with 29 trials.
Does levosimendan improve echocardiographic parameters of ventricular systolic and diastolic functions in heart failure patients?
Levosimendan is associated with improvements in echocardiographic parameters of both left and right ventricular systolic and diastolic functions in heart failure patients.
Long et al. (2021) studied this question.
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