Why the study?
Does combined glyceryl trinitrate and propranolol improve coronary haemodynamic and metabolic effects and prevent ischaemia compared to propranolol alone in patients with and without coronary disease?
Does combined glyceryl trinitrate and propranolol improve coronary haemodynamic and metabolic effects and prevent ischaemia compared to propranolol alone in patients with and without coronary disease?
The combination of glyceryl trinitrate and propranolol enhances tachycardia tolerance and prevents tachycardia-induced manifestations of ischaemia better than propranolol alone.
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May support combined therapy for tachycardia-induced ischemia; hypothesis-generating and requires randomized confirmation before practice change.
Schang et al. (1978) studied this question.
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