Why the study?
Does a high comorbidity burden (CCI ≥3) reduce the quality of INR control in elderly patients with non-valvular atrial fibrillation treated with VKA?
Population
2,164 patients aged 80 and over with non-valvular atrial fibrillation treated with vitamin K antagonists in…
Comparison
High burden of comorbidities, defined by a… vs Lower burden of comorbidities (CCI < 3)
Design
Cross-sectional
Authors
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May warrant closer INR monitoring in comorbid elderly AF patients on VKA; leaves open causal direction and intervention effects.
Does a high comorbidity burden (CCI ≥3) reduce the quality of INR control in elderly patients with non-valvular atrial fibrillation treated with VKA?
In elderly patients with non-valvular atrial fibrillation on vitamin K antagonists, a higher comorbidity burden (CCI ≥3) is significantly associated with poorer INR control.
Rouaud et al. (2015) studied this question.
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