Why the study?
Does synthetic alpha-human atrial natriuretic peptide infusion alter hemodynamic parameters in healthy volunteers?
Population
11 healthy volunteers
Comparison
Synthetic alpha-human atrial natriuretic peptide… vs Placebo
Design
Double-blind
Follow-up
30 min postinfusion
Authors
Loading...
May enhance hemodynamics in healthy volunteers; hypothesis-generating for therapeutic use in heart failure or hypertension.
Does synthetic alpha-human atrial natriuretic peptide infusion alter hemodynamic parameters in healthy volunteers?
Short infusion of alpha-hANP causes peripheral arterial vasodilation and improves cardiac pump function by reducing left ventricular afterload in healthy volunteers.
Hynynen et al. (1988) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: