Why the study?
Does isradipine sustained release administered in the morning versus evening reduce 24 h ambulatory blood pressure in patients with uncomplicated essential hypertension?
Does isradipine sustained release administered in the morning versus evening reduce 24 h ambulatory blood pressure in patients with uncomplicated essential hypertension?
Isradipine sustained release 5 mg once daily effectively lowers 24-hour ambulatory blood pressure similarly whether administered in the morning or evening.
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Supports flexible morning or evening dosing of isradipine SR; confirms timing independence for 24-h BP control in essential hypertension.
Fogari et al. (1993) studied this question.
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