Why the study?
Does isradipine MR once daily reduce 24-hour ambulatory blood pressure in patients with essential hypertension?
Population
32 patients across two studies (10 with mild-to-moderate hypertension, 22 with essential hypertension)
Comparison
Isradipine modified-release once daily or… vs Placebo
Design
Other
Follow-up
24 hours
Authors
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Supports once-daily isradipine MR for 24-h BP reduction in hypertension; leaves open comparative trials versus other agents.
Does isradipine MR once daily reduce 24-hour ambulatory blood pressure in patients with essential hypertension?
Low-dose isradipine modified-release once daily effectively reduces 24-hour ambulatory blood pressure in patients with essential hypertension.
Diemont et al. (1991) studied this question.
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