Why the study?
Does isradipine 2.5 mg twice daily reduce 24-hour arterial blood pressure in untreated essential hypertensives?
Population
11 untreated essential hypertensives
Comparison
Isradipine 2.5 mg twice daily for 4 weeks vs Placebo for 4 weeks
Design
RCT, random order, double-blind
Follow-up
4 weeks
Authors
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Supports isradipine 2.5 mg BID for 24-h BP control in untreated essential hypertension; confirms dihydropyridine CCB efficacy in this RCT population.
Does isradipine 2.5 mg twice daily reduce 24-hour arterial blood pressure in untreated essential hypertensives?
Isradipine 2.5 mg twice daily significantly reduces 24-hour systolic and diastolic blood pressure in untreated essential hypertension.
Low et al. (1993) studied this question.
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