Why the study?
Does isradipine reduce blood pressure in patients with essential hypertension?
Population
24 patients with essential hypertension
Comparison
Isradipine after an initial 3-week baseline… vs Placebo throughout the entire study
Design
RCT, randomized, double-blind, placebo-controlled
Follow-up
3 weeks of active treatment
Authors
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Supports isradipine 20 mg daily in essential hypertension; confirms BP-lowering efficacy in this RCT.
Does isradipine reduce blood pressure in patients with essential hypertension?
Isradipine is an effective antihypertensive agent that lowers blood pressure without inducing reflex tachycardia.
Nelson et al. (1986) studied this question.
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