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Background: Management of moderate to advanced furcation defects presents a major challenge in periodontal therapy. Conventional treatments like root resection have led to limited success which led to attempts of regenerative therapy which can result in bone fill and closure of defects. Aim and objective: To compare the outcomes of hydroxyapatite (HA)/beta-tricalcium phosphate (BTCP) with bioabsorbable collagen membrane (test group) to open flap debridement (OFD) (control) in the management of human mandibular class II furcation defects radiographically. Materials and methods: A total of 20 furcation involvement sites (10 tests and 10 controls) were treated in this randomized clinical trial. Test groups were treated with OSSIFI (HA/BTCP) and HEALIGUIDE (collagen membrane). Control groups were treated with OFD alone. Defect depth, defect fill, and defect fill percentage were measured radiographically. p value <0.05 was considered significant. Results: After 6 months, radiographic measurements showed a significant defect fill of 1.69 0.55 and 1.18 0.32 in test and control groups, respectively. The test group showed statistically significant improvements.
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Manohar et al. (2021) studied this question.
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