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November 10, 2020Journal of obstetrics and gynaecology research

Laparoscopic adenomyomectomy combined with levonorgestrel‐releasing intrauterine system in the treatment of adenomyosis: Feasibility and effectiveness

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Authors

FSFeng SunMicrosoft (United States)YZYe ZhangZhejiang Chinese Medical UniversityMYMin YouQingdao University

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Implication

Case series shows laparoscopic adenomyomectomy with an intrauterine device significantly reduces pain and bleeding in adenomyosis, indicating a viable uterus-sparing approach.

Key Points

  • To assess the clinical efficacy and safety of laparoscopic adenomyomectomy combined with intraoperative placement of a levonorgestrel-releasing intrauterine system for symptomatic adenomyosis.
  • Conducted a university medical center case-series study of 52 patients with symptomatic adenomyosis treated between January 2015 and July 2018.
  • Evaluated changes in visual analog scale scores, menstrual flow, uterine volume, and adverse events preoperatively and at 3, 12, and 24 months postoperatively.
  • Mean visual analog scale scores, menstrual flow scores, and uterine volume decreased significantly at 3, 12, and 24 months post-surgery compared with preoperative baselines (all P < 0.001).
  • Clinical effectiveness rates were 98% at 3 months and 96% at 12 and 24 months for dysmenorrhea, and 97.6% at 3 months and 95.2% at 12 and 24 months for menorrhagia.
  • Reported adverse events included amenorrhea in 23.1% (n = 12), device expulsion in 3.8% (n = 2), and uterine perforation in 1.9% (n = 1), with no surgical conversions to laparotomy.

Cite This Study

Sun et al. (2020) studied this question.

synapsesocial.com/papers/6a71557c8031ec7bb1dce6fbhttps://doi.org/10.1111/jog.14571
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  1. 1How can we measure endometriosis-associated pelvic pain?2012 · 23 citations
  2. 2Efficacy of laparoscopic adenomyomectomy using double-flap method for diffuse uterine adenomyosis2015 · 54 citations
  3. 3Hysteroscopic excision of symptomatic myometrial adenomyosis: feasibility and effectiveness2017 · 16 citations
  4. 4Efficacy of Combined Levonorgestrel-Releasing Intrauterine System with Gonadotropin-Releasing Hormone Analog for the Treatment of Adenomyosis2013 · 54 citations
  5. 5The Efficacy, Side-Effects and Continuation Rates in Women With Symptomatic Endometriosis Undergoing Treatment With an Intra-uterine Administered Progestogen (Levonorgestrel): A 3 Year Follow-up2005 · 24 citations