Why the study?
It was not established whether CT-based vascular pruning correlates with histologic arterial remodeling in pulmonary hypertension.
Does CT-based vascular pruning correlate with histologic arterial remodeling in patients undergoing resection for early-stage lung adenocarcinoma?
Population
138 patients who underwent resection for early-stage lung adenocarcinoma
Comparison
CT-based vascular pruning (BV5/TBV) vs histologic arterial remodeling (VWA%)
Design
Observational cross-sectional study
Authors
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CT pruning may reflect histologic remodeling in select patients; leaves open validation as noninvasive marker in pulmonary hypertension.
Does CT-based vascular pruning correlate with histologic arterial remodeling in patients undergoing resection for early-stage lung adenocarcinoma?
CT-based measures of vascular pruning correlate significantly with histologic arterial remodeling, suggesting CT may serve as a non-invasive indicator of pulmonary vascular pathology.
Synn et al. (2021) studied this question.
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