Coronary artery branching patterns and vessel characteristics directly influence the structural organization of the intima, which may have implications for understanding localized vascular changes.
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May inform vessel-specific atherosclerosis models; leaves open clinical translation in prospective cohorts.
A study on 22 pairs, including subjects of similar age, sex and cause of death but with different branching anatomical patterns, shows, that the amount and structural organization of elastic and muscular tissue of the thickened intima are strongly influenced by (a) the size, length, mode of ramification of the parent vessels of the coronary tree; (b) the number of branch orifices in a given arterial segment, and (c) the collateral or terminal character of certain daughter branches.
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Velican et al. (1978) studied this question.
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