Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
May 21, 2007Annals of SurgeryOpen Access

A Prospective Randomized Controlled Trial of Multimodal Perioperative Management Protocol in Patients Undergoing Elective Colorectal Resection for Cancer

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does a multimodal perioperative management protocol reduce postoperative stay in patients undergoing elective colorectal resection for cancer?

Population

70 patients undergoing elective colorectal resection for cancer, stratified by sex and requirement for total…

Comparison

Multimodal perioperative management protocol vs Control management

Design

RCT, Centrally randomized, stratified by sex and requirement for a total…

Follow-up

Postoperative period

Authors

CKChun Kheng KhooMusgrove Park HospitalCVChristopher VickeryMusgrove Park HospitalNFNicola ForsythEngeneic (Australia)

Discussion

Loading...

Member takes

Implication

Supports multimodal perioperative protocols for shorter stays after colorectal cancer resection; confirms RCT benefits without added morbidity.

Structured PICO

Does a multimodal perioperative management protocol reduce postoperative stay in patients undergoing elective colorectal resection for cancer?

P
Population
70 patients undergoing elective colorectal resection for cancer, stratified by sex and requirement for total mesorectal excision (TME). Median ages 69.3 vs. 73.0 years.
I
Intervention
Multimodal perioperative management protocol (intravenous fluid restriction, unrestricted oral intake with prokinetic agents, early ambulation, and fixed regimen epidural analgesia)
C
Comparator
Control management (intravenous fluids to prevent oliguria, restricted oral intake until return of bowel motility, and weaning regimen epidural analgesia)
O
Outcome
Postoperative stay and achievement of independence milestones

A multimodal perioperative management protocol significantly reduces postoperative length of stay following elective colorectal cancer surgery without increasing overall morbidity or mortality.

Cite This Study

Khoo et al. (2007) studied this question.

synapsesocial.com/papers/6a71597ae36a167817e32ea5https://doi.org/10.1097/01.sla.0000259219.08209.36
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Thoracic epidural anaesthesia and analgesia: United Kingdom practice2000 · 33 citations
  2. 2Fluid Shifts during the Surgical Period1966 · 44 citations
  3. 3Is Early Oral Feeding Safe After Elective Colorectal Surgery? A Prospective Randomized Trial1995 · 407 citations