In patients with labile hypertension, aging is associated with increased daytime systolic blood pressure variability, widened pulse pressure, and abnormal diurnal patterns.
Should not yet change BP monitoring in labile hypertension; hypothesis-generating for longitudinal studies on age-related BPV.
From 88 subjects with labile high blood pressure (LHBP), we collected blood pressure variability (BPV) and assessed relationships with age, medications, and nocturnal pattern via ambulatory blood pressure monitoring. The average age of the subjects was 64 ± 13 years and they were on 1.5 ± 1.3 antihypertensives. BPV did not differ diurnally and was not influenced by medication. Aging associates with increasing daytime systolic but not diastolic BPV, with increasing nighttime systolic BP, and decreasing diastolic BP diurnally. Subjects had widened pulse pressure and abnormal diurnal pattern with age. Further studies are needed to stratify an individual's risk associated with LHBP.
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Elliott et al. (2012) studied this question.
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