Why the study?
Does equilibrium contrast-enhanced CT accurately measure myocardial extracellular volume fraction compared to histologic findings and MRI in patients with severe aortic stenosis?
Does equilibrium contrast-enhanced CT accurately measure myocardial extracellular volume fraction compared to histologic findings and MRI in patients with severe aortic stenosis?
Equilibrium contrast-enhanced CT can accurately measure myocardial extracellular volume fraction, correlating well with both histologic fibrosis quantification and MRI-derived ECV in patients with severe aortic stenosis.
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May support CT ECV for fibrosis assessment in severe aortic stenosis; extends MRI correlations but leaves validation open pending prospective trials.
Bandula et al. (2013) studied this question.
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