Why the study?
Does intracoronary fasudil prevent acetylcholine-induced coronary artery spasm in patients with vasospastic angina?
Does intracoronary fasudil prevent acetylcholine-induced coronary artery spasm in patients with vasospastic angina?
Intracoronary administration of the Rho-kinase inhibitor fasudil effectively prevents acetylcholine-induced coronary artery spasm and associated myocardial ischemia in patients with vasospastic angina.
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May prevent ACh-induced spasm and ischemia in vasospastic angina; hypothesis-generating and requires randomized confirmation.
Masumoto et al. (2002) studied this question.
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