Population
Guinea-pig extrapulmonary vein striated muscle fibers
Comparison
Application of cations and catecholamines and… vs Atrial muscle fibers
Design
Preclinical
Authors
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Adrenergic-evoked extrapulmonary vein activity may trigger atrial arrhythmias; hypothesis-generating in guinea-pig model and leaves open human relevance.
Epinephrine and isoproterenol can evoke pacemaker activity in guinea-pig extrapulmonary vein striated muscle cells, which can propagate retrogradely to the atrium.
Hakaru Tasaki (1969) studied this question.
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