January 1, 2001Clinical and Experimental Hypertension

Examination of Angiotensin Ii Type 1 and Type 2 Receptor Expression in Human Kidneys by Immunohistochemistry

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Population

21 human kidney samples from patients with and without glomerular lesions

Design

Cross-sectional

Authors

MMMizuo MifuneFujifilm (Japan)HSHiroyuki SasamuraKeio University YNYuichi NAKAZATONippon Institute of Technology

Discussion

Member takes

Implication

Does not alter clinical management; extends localization data to human glomerular disease but leaves functional and therapeutic roles open.

Structured PICO

Population

21 human kidney samples from patients with and without glomerular lesions (3 controls undergoing nephrectomy, 4 minimal change disease, 6 IgA nephropathy, 8 membranous glomerulonephritis)

Outcome

Distribution of angiotensin II type 1 (AT1) and type 2 (AT2) receptors by immunohistochemistrysurrogate

AT1 and AT2 receptors are expressed in both normal and diseased human kidneys, supporting their potential physiological role in renal function.

Cite This Study

Mifune et al. (2001) studied this question.

synapsesocial.com/papers/6a7162e8ac440176ef2a1065 https://doi.org/10.1081/ceh-100102664

View Full Paper

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Implication

Does not alter clinical management; extends localization data to human glomerular disease but leaves functional and therapeutic roles open.

Examination of Angiotensin Ii Type 1 and Type 2 Receptor Expression in Human Kidneys by Immunohistochemistry

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Examination of Angiotensin Ii Type 1 and Type 2 Receptor Expression in Human Kidneys by Immunohistochemistry

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider