Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
December 14, 2024CureusOpen Access

Despite initial stabilization with transfusions, the patient developed hemodynamic instability, was found to have a large ventricular septal defect (VSD) on echocardiography, and ultimately died.

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Managing ACS in patients with recent gastrointestinal bleeding presents a clinical dilemma balancing ischemic risk and life-threatening rebleeding, complicating the use of standard DAPT.

Population

An 80-year-old female with Klatskin tumor resection, recurrent GI bleeding, and severe anemia presenting with ACS

Design

Case report

Authors

JOJesse O'RorkeGBGreyson ButlerRCRamesh Chandra

Discussion

Loading...

Member takes

Overview

Optimal antiplatelet strategy after ACS with recent GI bleed remains uncertain; this Level 5 report leaves open need for prospective data.

Structured PICO

P
Population
80-year-old female with a history of Klatskin tumor resection, duodenal ulcer, recurrent gastrointestinal bleeding, and severe anemia (hemoglobin 5.7 g/dL) presenting with anterolateral ST-elevation myocardial infarction (STEMI)
I
Intervention
Conservative management including aspirin monotherapy and supportive care (transfusions)
O
Outcome
Clinical course and mortality (development of ventricular septal defect and death)

This case highlights the extreme difficulty of managing STEMI in patients with severe anemia and recent GI bleeding, where conservative management may be necessary but carries a high risk of mechanical complications like VSD.

Cite This Study

O'Rorke et al. (2024) studied this question.

synapsesocial.com/papers/6a716357f44fa9f079df2f5fhttps://doi.org/10.7759/cureus.75699
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Managing Acute Myocardial Infarction in Shock and Anemia2025
  2. 2Management of Patient with Simultaneous Overt Gastrointestinal Bleeding and Myocardial Infarction with ST-Segment Elevation – Priority Endoscopy2021 · 1 citations
  3. 3Invasive Strategy of STEMI in Patients with TAVB, RBBB, and Dual High-Risk Profiles: Navigating the Challenges of Antithrombotic Therapy – A Case Report2025
  4. 4Transcatheter Management of Severe Aortic Stenosis, Acute Pulmonary Embolism, and Gastrointestinal Bleeding2026
  5. 5Salvage treatment for severe upper gastrointestinal bleeding caused by Mallory-Weiss syndrome and myocardial depression after acute myocardial infarction2022 · 1 citations