Why the study?
Does triple antithrombotic therapy reduce MACCE in patients with atrial fibrillation undergoing drug-eluting stent implantation compared to dual antiplatelet therapy or warfarin plus a single antiplatelet agent?
Population
622 consecutive patients with atrial fibrillation (AF) undergoing drug-eluting stent (DES) implantation.
Comparison
Triple antithrombotic therapy comprising… vs Dual antiplatelet therapy or warfarin plus a…
Design
Cohort
Authors
Loading...
Triple therapy was associated with lower MACCE without excess bleeding in AF patients post-DES; leaves open need for randomized confirmation before practice change.
Does triple antithrombotic therapy reduce MACCE in patients with atrial fibrillation undergoing drug-eluting stent implantation compared to dual antiplatelet therapy or warfarin plus a single antiplatelet agent?
Triple antithrombotic therapy with closely monitored INR reduces MACCE without significantly increasing major bleeding in AF patients undergoing DES implantation.
Gao et al. (2010) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: