What question did this study set out to answer?

To examine whether excretion of a sodium-retaining factor and 11-oxysteroids changes during toxemic pregnancies in diabetic and non-diabetic patients.

October 1, 1951Experimental Biology and Medicine

Evidence for a Sodium Retaining Factor in Toxemia of Pregnancy.

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Authors

JCJ. J. ChartNovartis (Switzerland)ESElva G. ShipleyUniversity of Wisconsin–Madison EGEdgar GordonVanderbilt University Medical Center

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Implication

Observational study reveals marked increases in sodium-retaining factor excretion in pregnant women with toxemia, indicating a potential early driver and biomarker of disease.

Key Points

To examine whether excretion of a sodium-retaining factor and 11-oxysteroids changes during toxemic pregnancies in diabetic and non-diabetic patients.
Evaluated excretion levels of a sodium-retaining factor alongside 11-oxysteroids in diabetic and non-diabetic pregnant patients with or developing toxemia.
Excretion of a sodium-retaining factor rose markedly in toxemic pregnancies across both diabetic and non-diabetic cohorts.
Increased excretion of the sodium-retaining factor was detected prior to the onset of overt toxemic symptoms in one patient, whereas 11-oxysteroid excretion exhibited no parallel increase.

Cite This Study

Chart et al. (1951) studied this question.

synapsesocial.com/papers/6a71652075498292b70adff2 https://doi.org/10.3181/00379727-78-19035

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Implication

Observational study reveals marked increases in sodium-retaining factor excretion in pregnant women with toxemia, indicating a potential early driver and biomarker of disease.

Evidence for a Sodium Retaining Factor in Toxemia of Pregnancy.

Discussion

Member takes

Implication

Key Points

Cite This Study

Evidence for a Sodium Retaining Factor in Toxemia of Pregnancy.

Discussion

Member takes

Implication

Key Points

Cite This Study

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