Population
18 spontaneous, guanidine-resistant mutants of poliovirus
Design
Preclinical
Authors
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pX mutations may determine poliovirus guanidine resistance; hypothesis-generating in animal models and requires validation.
The 37-kilodalton protein pX likely plays a role in determining the guanidine resistance trait of poliovirus.
Anderson-Sillman et al. (1984) studied this question.
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