Why the study?
Does growth hormone therapy improve psychosocial adaptation in non-growth-hormone-deficient children with short stature?
Does growth hormone therapy improve psychosocial adaptation in non-growth-hormone-deficient children with short stature?
Psychosocial adaptation to short stature is generally good, and current evidence does not support using growth hormone therapy solely for psychosocial indications in non-growth-hormone-deficient children.
Caution against growth hormone therapy for psychosocial indications alone in short stature; leaves open need for prospective trials in non-deficient children.
Although growth hormone does not clearly improve final height in non-growth-hormone-deficient children with short stature, it leads to a temporary acceleration of growth velocity. It is an ongoing discussion whether this effect supports psychosocial adaptation to short stature and therefore could be an indication for growth hormone treatment in children with short stature without growth hormone deficiency. We have reviewed recent literature concerning psychosocial consequences of short stature. Together with own data we can demonstrate that short people regularly adapt well to their height and have a good self-esteem. On the other hand, we focus on the problem that most studies on this subject suffer from methodical problems. A growth-related questionnaire that evaluates subjective and objective perceptions of being short in patients and peers is not at hand. As a consequence, psychosocial problems due to short stature have not been exactly classified yet and therefore do not represent an indication for growth hormone therapy.
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Thorsten Wygold (2002) studied this question.
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