Why the study?
Does prolonged treadmill exercise produce reproducible alterations in cardiac biomarkers (hs-cTnT and NT-proBNP) in young athletes?
Does prolonged treadmill exercise produce reproducible alterations in cardiac biomarkers (hs-cTnT and NT-proBNP) in young athletes?
Prolonged exercise in young athletes induces a consistent but blunted hs-cTnT release upon repeated bouts, whereas NT-proBNP responses are not reproducible.
hs-cTnT responses to repeated exercise may be reproducible yet blunted in athletes; leaves open NT-proBNP utility and clinical relevance.
We examined the reproducibility of alterations in cardiac biomarkers after two identical bouts of prolonged exercise in young athletes. Serum high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP) levels were assessed before and after exercise. Significant rises in median hs-cTnT and NT-proBNP occurred in both trials. While the absolute changes in hs-cTnT were smaller after trial 2, the pattern of change was similar and the delta scores were significantly related. However, the change in NT-proBNP was not correlated between trials. The hs-cTnT release demonstrates some consistency after exercise although the blunted hc-cTnT response requires further study.
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Tian et al. (2014) studied this question.
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