Liver Protein Synthesis after Partial Hepatectomy and Acute Stress

Partial hepatectomy and acute stress (intraperitoneal injection of Celite) cause increases in the rates of synthesis of serum albumin and fibrinogen, proteins that are formed mainly or entirely by the liver. The rises in protein synthesis after removal of part of the liver differ kinetically from those after acute stress. In addition, only the response to partial hepatectomy is independent of the adrenal glands. Both responses seem to be related to an increase in the ability of liver polyribosomes to form protein.