Why the study?
Does sequential pulse defibrillation reduce the minimum defibrillation energy compared to single pulse defibrillation in a pig model?
Population
Open-chest halothane-anesthetized pigs
Comparison
Sequential pulse shocks with varying separation… vs Single pulse shocks
Design
Preclinical
Authors
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May lower defibrillation energy in animals; hypothesis-generating for human ICD optimization, pending trials.
Does sequential pulse defibrillation reduce the minimum defibrillation energy compared to single pulse defibrillation in a pig model?
Sequential pulse defibrillation with an optimal 0.2 ms separation significantly reduces the energy required for internal cardiac defibrillation in a porcine model compared to single pulses.
Jones et al. (1987) studied this question.
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