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For many years coronary occlusion was considered a disease of old age and emphasis was laid on the marked discrepancy in its incidence between the sexes. More recently, as the diagnosis of occlusion has become more precise, there has been an increasing number of reports of its occurrence in persons in the younger age groups and in women as well as men. Conner and Holt¹and, later, Bean²took into consideration certain factors of age and sex in their discussion of the prognosis and course of the disease. In view of the extreme importance of coronary occlusion, a large series of cases observed by us has been analyzed with a view to determining the influence of age, sex and hypertension on the incidence and prognosis of the disease as well as on its various clinical manifestations. In addition, particular attention has been paid to the relation of hypertension
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Arthur M. Mastér (1939) studied this question.
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