Why the study?
Do NSAIDs influence the effects of antihypertensive drugs?
Do NSAIDs influence the effects of antihypertensive drugs?
NSAIDs (except sulindac) can attenuate the blood pressure-lowering effects of beta-blockers and captopril, highlighting a clinically important drug interaction.
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May warrant vigilance with most NSAIDs in treated hypertension; leaves open prospective trials to quantify effects.
Jaegerc et al. (1986) studied this question.
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