Why the study?
Does omega-3 fatty acid supplementation improve blood pressure and haemorheological parameters in healthy subjects?
Does omega-3 fatty acid supplementation improve blood pressure and haemorheological parameters in healthy subjects?
High-dose omega-3 fatty acid supplementation (2.52 g daily) significantly reduces systolic blood pressure and improves haemorheological parameters in healthy subjects over 5 weeks.
Supports omega-3 for primary prevention in healthy adults; extends RCT evidence to haemorheological parameters.
The effects of a fish oil concentrate with an omega-3 fatty acid content of 42% was determined in two dosages in a double-blind, placebo-controlled study with a parallel group comparison over a period of 5 weeks with 30 healthy subjects. The daily intake chosen was four and eight capsules corresponding to 1.26 or 2.52 g omega-3 fatty acids. Plasma viscosity, erythrocyte rigidity and systolic blood pressure were significantly decreased (p less than 0.01) after a 5-week administration of 2.52 g omega-3 fatty acid daily. The reduction in vitamin E concentration was significant (p less than 0.01) only in the low-dose fish oil group. Lipids and lipoproteins remained unchanged throughout this experiment.
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Bach et al. (1989) studied this question.
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