Why the study?
Does the PAT III device detect differences in spontaneous platelet aggregation between diabetic patients and healthy controls?
Population
146 healthy individuals and 327 diabetic patients
Comparison
Photometric platelet aggregation test (PAT III) vs Healthy individuals (for the diabetic group)
Design
Cross-sectional
Authors
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May signal elevated thrombotic risk in diabetes; hypothesis-generating and requires prospective validation before clinical adoption.
Does the PAT III device detect differences in spontaneous platelet aggregation between diabetic patients and healthy controls?
The PAT III device can reliably measure spontaneous platelet aggregation, demonstrating increased aggregation in diabetic patients compared to healthy controls.
Breddin et al. (1976) studied this question.
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