Why the study?
Does prolonged exercise alter left ventricular contractile function in healthy middle-aged men?
Population
12 healthy middle-aged men, mean age 43.5 +/- 1.9 years, maximal O2 uptake (Vo2max) 51.7 +/- 1.5 ml.kg-1.min-1
Comparison
Cycling for 120 minutes at 65% Vo2max vs Baseline (pre-exercise)
Design
Cohort
Follow-up
150 minutes (120 minutes exercise plus 30 minutes recovery)
Authors
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SV falls via preload reduction without contractility loss after prolonged exercise; leaves open relevance in patients or longer durations.
Does prolonged exercise alter left ventricular contractile function in healthy middle-aged men?
Prolonged exercise in healthy middle-aged men reduces stroke volume due to decreased preload rather than impaired left ventricular contractility.
Goodman et al. (2008) studied this question.
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